False-the best way to prevent a cold is to regularly wash or sanitize your hands. much of the illness and death caused by influenza can be prevented by annual influenza vaccination. to prevent flu, vaccination is recommended. flu vaccine (influenza vaccine made from inactivated and sometimes attenuated [non-infective] virus) is specifically recommended for those who are at high risk for developing serious complications as a result of influenza infection. these high-risk groups for conventional flu include all people aged 65 years or older and people of any age with chronic diseases of the heart, lung, or kidneys; diabetes; immunosuppression; or severe forms of anemia.