Amphotericin b-the correct answer is a. blastomycosis can present with fl u-like symptoms, fevers, chills, productive cough, myalgia, arthralgia, and pleuritic chest pain. some patients will fail to recover from an acute infection and progress to develop chronic pulmonary infection or widespread disseminated infection. fluconazole or ketoconazole is used for the treatment of local blastomycosis infections, and amphotericin b is used for the treatment of systemic infections.
answer b is incorrect. fluconazole or ketoconazole are effective treatments for local blastomycosis infections but are ineffective if the infection is systemic. systemic infections require amphotericin b.
answer c is incorrect. itraconazole or potassium iodide is used for the treatment of sporothrix
schenckii. s. schenckii is the cause of sporotrichosis. when s. schenckii is introduced into the skin, usually by a thorn prick, it causes a local pustule or ulcer with nodules along draining lymphatics (ascending lymphangitis). s. schenckii is a dimorphic fungus that has cigar-shaped budding yeast visible in pus.
answer d is incorrect. sodium stibogluconate is used to treat leishmania donovani infection.
l. donovani presents with hepatomegaly and splenomegaly, malaise, anemia, and weight loss.
l. donovani is transmitted via the sandfly. microscopically, macrophages containing amastigotes are observed.
answer e is incorrect. topical miconazole or selenium sulfide (selsun) is used to treat malassezia furfur. m. furfur is the cause of tinea versicolor. symptoms of this infection include hypopigmented skin lesions that occur in hot and humid conditions.
