The sliding filament hypothesis describes the process of muscle contraction based on muscle proteins that slide past each other to generate movement. It was introduced in 1954 by two research teams.
According to the sliding filament premise, the myosin filaments of muscle fibers slide past the actin filaments throughout muscle contraction, while the two groups of filament remain at a relatively constant length. The sliding filament theory is the term for the process that describes how thin filament to generate muscle contraction.
A series of steps take place so that the muscle can generate the tension required to contrast. The length of concentration depends upon how much ATP and calcium are present. The concentration of muscle is what makes movement possible. This theory describes the way a muscle cell contracts or shortens.
Should include:calcium released by the cisternae of the sr binds to troponin causing a confirmational change in the troponinthe aforementioned change causes the troponin/tropomyosin to move, exposing the myosin binding site to be exposed on the actinatp from the sarcoplasm binds to the myosin head, causing myosin to release actinatpase on the myosin head hydrolysis atp into adp and pi, which causes myosin to assume the cocked positionmyosin, containing adp and pi can cross-link with actinnow the energy from the hydolyzed phosphate bond is converted into mechanical energy and myosin pulls actin towards the center of the sarcomere, which causes the release of adp and pinow atp can bind, causing disruption of the cross-linking, which allows this process to repeat as long as atp and ca++ are presentin the absence of ca++, the myosin will remain in the cocked position, until ca++ raisestermination of the signal occurs when:action potential stops and ca++ within the motor neuron is pumped back out of the cell by active trasportaction potential stops and causes intracellular ca++ to be pumped back into the sr via active x-portach vesicles no longer undergo exocytosisachase breaks down achintracellular ca++ to be pumped back into the sr via active x-port