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Which of the following drugs would be appropriate for a systemic antifungal treatment of this patient?
A 68-year-old man is in the hospital because of a prostatectomy performed 4 days before. He is wearing a urinary catheter and is currently treated with a combination of broad spectrum antibiotics. The patient has been suffering from chronic renal insufficiency for the past two years. Two recent urinalysis show many budding yeasts and cultures were positive for Candida albicans.



A. Amphotericin B
B. Fluconazole
C. Piperacillin
D. Metronidazole
E. Griseofulvin
F. Nystatin

This question is part of block 15 pharm antifungal drugs

Asked by Summer, Last updated: Sep 08, 2020

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1 Answer

John Smith

John Smith

John Smith
John Smith

Answered Sep 09, 2016

Fluconazole-answer: b the patient is suffering from candiduria, a condition often related to the placement of an indwelling urinary catheter, especially if the patient is taking brad spectrum antibiotics, like in the present case. eradication of candida in the urine includes the removal of the catheter and an antifungal treatment. treatment options include amphotericin b or fluconazole. however, in the present patient, amphotericin b, which directly damages renal tubules, is contraindicated because of chronic renal dysfunction. a) (see explanation above) c, d) these agents are not antifungal drugs. e) this antifungal drug is not effective against candida albicans. f) nystatin is effective against candida albicans but is too toxic to be used systemically.
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