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Which of the following statements correctly pair the antifungal drugs with their likely mechanism of action?



A. Amphotericin B - inhibits thymidylate synthetase
B. Griseofulvin - interferes with microtubule function
C. Flucytosine - inhibits fungal mycolic acid synthesis
D. Miconazole - inhibits DNA dependent RNA polymerase
E. Nystatin - inhibits ergosterol synthesis
F. Terbinafine - inhibits squalene epoxidase

This question is part of block 15 pharm antifungal drugs

Asked by Hartwell, Last updated: Sep 12, 2020

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3 Answers

John Adney

John Adney

John Adney
John Adney

Answered May 25, 2017

Both are false because you do not explain in particle why thats why it is rong
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John Adney

John Adney

John Adney
John Adney

Answered Nov 26, 2016

2 +6
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John Smith

John Smith

John Smith
John Smith

Answered Sep 09, 2016

Griseofulvin - interferes with microtubule function-2. terbinafine - inhibits squalene epoxidase-answer: bf griseofulvin is effective only against dermatophytes which take up the drug via an active transport system. its exact mechanism of action is still unclear but the drug appears to disrupt the mitotic spindle trough interaction with microtubules. terbinafine (also effective mainly against dermatophytes) blocks the conversion of squalene to lanosterol by inhibiting the fungal enzyme squalene epoxidase a) inhibition of thymidylate synthetase would be the mechanism of action of flucytosine. c) inhibition of mycolic acid synthesis would be the mechanism of action of isoniazid. d) inhibition of dna dependent rna polymerase would be the mechanism of action of rifampin e) inhibition of ergosterol synthesis would be the mechanism of action of azoles.
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