Gangrenous necrosis-(c) severe peripheral atherosclerotic disease is a common complication of long-standing diabetes mellitus.
atherosclerotic narrowing of the arteries to the lower legs can cause ischemia and gangrene. the foot is often involved
with gangrene, which may necessitate amputation. diabetic neuropathy with decreased sensation increases the risk of
repeated trauma, which enhances the risk of ulcerations that cause infection and inflammation that promotes gangrene.
although pancreatic islets may have amyloid deposits, systemic amyloidosis and chronic pancreatitis (which involves the
parenchymal acini) do not occur with type 2 diabetes mellitus. patients with type 2 diabetes mellitus or obesity, or both, are
at increased risk of developing nonalcoholic steatohepatitis. because this patient is not taking medications such as insulin,
it is unlikely that he could become severely hypoglycemic. because he is overweight, it is more likely that he has type 2
diabetes mellitus; ketoacidosis is unlikely. infections with mucor circinelloides are more likely to occur in ketoacidosis.
bp7 649bp8 781782pbd7 11991200pbd8 11381139
