What will be the hepatic clearance of the drug (in mL/min)?

1200-5) learning objective: calculate the hepatic clearance of a drug, given sufficient dataanswer cby definition clearance is the volume of blood from which all the drug is removed per unit time. ifall the drug were removed by the liver, the liver clearance would equate the liver blood flow(volume per unit time), i.e 1500 ml/min. since 20% of the drug can reach the general circulation itfollows that 80% of the drug is removed by the liver, that is the drug contained in 80% of the bloodflow. therefore the liver clearance will be 80% of the liver blood flow.