Which nephron site will have the tubular fluid/plasma (TF/P) - ProProfs Discuss
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Which nephron site will have the tubular fluid/plasma (TF/P) osmolarity lowest in a person who has been deprived of water?

Asked by Bertie, Last updated: Nov 27, 2020

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John Smith

John Smith

John Smith
John Smith

Answered Sep 09, 2016

D- a person who is deprived of water will have high circulating levels of antidiuretic hormone (adh). the tubular fluid/plasma (tf/p) osmolarity is 1.0 throughout the proximal tubule, regardless of adh status. in antidiuresis, tf/p osmolarity > 1.0 at site c because of equilibration of the tubular fluid with the large corticopapillary osmotic gradient. at site e, tf/p osmolarity > 1.0 because of water reabsorption out of the collecting ducts and equilibration with the corticopapillary gradient. at site d, the tubular fluid is diluted because nac1 is reabsorbed in the thick ascending limb without water, making tf/p osmolarity < 1.0.
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