Source- botulinum - infants: honey; adults: canned foodsource- tetani--spores in soils, especially those treated with manure.once the toxin is in the patient: for both of these cases, look at the endplate, synapse, and nmj. for tetanus toxin, the neurons have an inhibitory function; for botulinim they are active motor neurons. in the presence of toxin the release of hte neurotransmitter vesicles into the synapse is blocked. for butulinum toxin, the neurotransmitter is acetylcholine, motor neurons are blocked giving flaccid paralysis. for tetanus toxin, release of neurotransmitters activiating inhibitory neurons (gaba) are blocked resulting in continuous contraction.
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