It is due to the presence of memory b and t cells -a secondary immune response is more rapid, of longer duration, and more intense than the primary immune response and involves memory cells. humoral immunity and cell-mediated immunity involve retention of immunologic memory through memory b and t cells, respectively. a secondary immune response may involve memory t cells, helper cells, macrophages, and memory b cells. the proliferation of either t or b cells during the first exposure to antigen results in the production of memory cells. specificity is retained. for example, the introduction of a different (new) antigen induces a primary rather than a secondary response.
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