What is the most appropriate treatment in the following case? - ProProfs Discuss
Advertisement

What is the most appropriate treatment in the following case?

An 13 year old girl is referred by her GP with urinary symptoms. She has had dysuria and frequency for the last two weeks, and now has haematuria. She was empirically treated with antibiotics but with no improvement. Six months ago, she went on a two-week holiday in South Africa, where she swam most days in a lake near her cousins home. On microscopy of her urine, parasitic ova are seen.
1. Metronidazole
2. Mebendazole
3. Quinine
4. Albendazole
5. Praziquantel

Asked by Lucas, Last updated: Sep 24, 2022

+ Answer
Request
Question menu
Vote up Vote down

1 Answer

John Smith

John Smith

John Smith
John Smith

Answered Sep 08, 2016

Praziquantel-this girl has schistosomiasis, for which praziquantel is the recommended treatment. there are several species of this trematode which can infest humans, found in africa, south america, the caribbean, the middle east, and asia. transmission occurs when the schistosomal larvae (cercariae) are released by certain freshwater snails which they also infest. they burrow into the skin, often on the soles of the feet, and spread via the venous circulation to the lungs, from where they then pass into the systemic circulation. they are carried to the portal circulation where they mature, and progress to chronically infest the venous plexuses of either the bowel (s. japonicum, s. mansoni) or the bladder (s. haematobium). the eggs they release then migrate and are passed in the stools or urine, causing an intense granulomatous reaction. this can lead to ulceration or obstruction. ectopic deposition leads to symptoms affecting other organs. infestation is often asymptomatic, but may lead to presentation months or years. katayama fever is an acute serum-sickness like reaction seen several weeks following infestation.
upvote downvote
Reply 

Advertisement
Advertisement
Search for Google images Google Image Icon
Select a recommended image
Upload from your computer Loader
Image Preview
Search for Google images Google Image Icon
Select a recommended image
Upload from your computer Loader
Image Preview
Search for Google images Google Image Icon
Select a recommended image
Upload from your computer Loader

Email Sent
We have sent an email to your address "" with instructions to reset your password.