Mark Edward Fischbach was born in Honolulu, Hawaii, on June 28, 1989. His father met his mother when he was serving in the US military, and both moved to Cincinnati, Ohio, immediately after they gave birth to Fischbach. Markiplier grew up in Cincinnati, Ohio. He got his high school education at Milford High School. After his high school education, he went to the University of Cincinnati, where he studied biomedical engineering.
Unfortunately, he later dropped out of school to pursue his YouTube career. He started this when he created his first YouTube channel on March 6, 2012. His first video was uploaded on April 4, 2012. He started with the uploading of complete videos of indie and horror games. He couldn't sustain his first account because his Adsense account was banned. However, on May 26, 2012, he created another YouTube channel with the MarkiplierGAME. Markiplier now has millions of subscribers on his YouTube channel.