How are RNA hairpin turns related to termination?

The formation of the turns is achieved through complementary base pairing, thus leading to the separation of the RNA polymerase and RNA transcript. In Escherichia coli, the intrinsic termination of transcription needs the RNA hairpin to form in the nascent RNA.

This hairpin is relatively the major thing that enables the transcript and polymerase to be released on the DNA template at intrinsic termination sites. Intrinsic termination can be described as a process that is involved in prokaryotes. It mainly releases the RNA molecule that is newly constructed and also signals the end of transcription.

In prokaryotes like E. Coli, transcription is usually terminated, either by a rho-independent process or by a rho-dependent process. In the rho-dependent process, the function of the rho-protein is to locate and then bind the sequence of signals in mRNA. There is no need for a special protein in intrinsic termination to signal for termination, plus the particular sequences of RNA control it.

The hairpin loop forms in an mRNA strand during transcription and causes the RNA polymerase to dissociate from the DNA template strand. This process is called intrinsic termination, and the participating sequences are called terminator sequences.

The Stem-loop or hairpin loop occurs when regions of the same strand, typically complementary in nucleotide cycle when read in opposite directions, base-pair to form a double helix that results in an unpaired loop.

The composition becomes the critical building block of many RNA secondary structures. As an essential secondary structure of RNA, it can supervise RNA folding, protect structural stability for messenger RNA, offer recognition sites for RNA binding proteins, and operate as a substitute for enzymatic reactions.

The turns are formed because of the complementary base pairing for E. Coli. They will cause the separation of the RNA transcript and the RNA polymerase. When you say E. Coli, this is a type of bacteria that may live in your intestines. Some may say that this can also be found in the gut of some animals.

Some say that people can get this type of infection when they contact some items that are contaminated with this type of bacteria. There are some that may get E. Coli from the stools of humans or animals. Some may not even realize that E. Coli can also contact their water that they may consume.