Herpesviruses cause a wide spectrum of human disease. Eight identified human herpesviruses (HHV) include herpes simplex virus (type 1), HSV (type 2), varicella zoster virus (type 3), Epstein-Barr infectious mononucleosis virus (type 4), and cytomegalovirus (type 5). A sixth type (HHV-6) is identified as the causative agent of roseola (exanthema subitum), and a seventh (HHV-7) is serologically associated with several syndromes. Finally, human herpesvirus 8 (HHV-8) is linked with Kaposi sarcoma, primary effusion lymphoma, and some cases of multicentric Castleman disease.
Each persists in a latent state for the remainder of the persons life. With HSV and VZV, virus remains latent in sensory ganglia.
CURRENT MEDICAL DIAGNOSIS & TREATMENT 2019
o CHAPTER 32: VIRAL & RICKETTSIAL INFECTIONS
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