A 30 y/o woman, presented to her family physician complaining of - ProProfs Discuss
Cancel
TopicsDown
Products Down
Follow Us:
FacebookTwitter
Advertisement

A 30-y/o woman, presented to her family physician complaining of black, tarry stools. She had had a prosthetic valve replacement 4 months ago for severe aortic stenosis secondary to rheumatic disease and had been receiving daily anti-coagulant therapy since then. Physical examination revealed subconjunctival hemorrhage & bruises on ARMS & legs. Which of the following drugs most likely caused the patient’s symptoms and signs?

This question is part of Pharm anticoagulation drugs
Asked by Chachelly, Last updated: Sep 19, 2020

+ Answer
Request
Question menu
Vote up Vote down

1 Answer

Chachelly

Chachelly

Chachelly
Chachelly

Answered Sep 01, 2018

Warfarin

Learning objective: describe the main adverse effects of warfarin. Answer: D The primary approach to prevent valvular thrombosis and systemic thromboembolism associated with mechanical prosthetic valve replacement is a long-term anticoagulation with warfarin. Most likely the dose of warfarin was too high and therefore bleeding occurred, as pointed out by the symptoms and signs of the patient. A) Fibrinolytic drugs are not indicated for long-term prevention of thrombosis. B) Aspirin is sometimes used together with warfarin in patient with prosthetic valve mainly when evidence of thromboembolism exists despite adequate anticoagulation. However it is not effective for prevention when given alone. C, F) These drugs must be given parenterally and therefore are not suited for long-term anticoagulation. E) Aminocaproic acid is an antiplasmin drug and therefore would be contraindicated in this setting.
upvote downvote
Reply 

Advertisement
Advertisement
Search for Google images Google Image Icon
Select a recommended image
Upload from your computer Loader
Image Preview
Search for Google images Google Image Icon
Select a recommended image
Upload from your computer Loader
Image Preview
Search for Google images Google Image Icon
Select a recommended image
Upload from your computer Loader

Email Sent
We have sent an email to your address "" with instructions to reset your password.