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Which of the following types of antigen presenting cells (APCs) is specialized fordegradation and presentation of particulate antigens to T cells?




Asked by Smb, Last updated: Jul 28, 2021

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3 Answers

R. Barnes

R. Barnes

Always excited to learn and talk about new topics

R. Barnes
R. Barnes, Analyst, PhD, Clinton

Answered Jun 03, 2019

Macrophages are the type of Antigen Presenting Cells (APC) that are critical in the uptake and presentation of antigen to T cells. APC are specialized cells that show the antigen complex on their surfaces with major histocompatibility complexes (MHCs).

Macrophages, B cells and dendritic cells are termed “professional APC” as they present antigen to helper T cells. Macrophages are stimulated by interferon-gamma, which is secreted by T cell. This, in turn, causes the expression of MHC class II on the surface of macrophages and the secretion of many costimulatory molecules. Macrophages can engulf and phagocytose fragments of antigen and present them to helper T cells.

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W. Wright

W. Wright

Let's see how far my knowledge stretches

W. Wright
W. Wright, Biology student, Biology student, Astoria

Answered Apr 24, 2019

The answer to this is Macrophage. Are you wondering why this is the term used for this antigen? The word has been formed from two Greek words that mean “big eaters”. This type of white blood cell will make sure that the different debris, foreign substances, and so much more will be removed from the body so that they will not cause anything worse.

This will “eat” the viruses, bacteria, parasites, and fungi that do not belong in the body so that the body can stay healthy. It is obvious that the macrophage may not do exactly what it is supposed to do. It may not have the ability to get rid of the foreign substances in the body.

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smb6

smb

smb6
Smb

Answered Aug 28, 2018

Macrophage
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