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Pharmacology Questions and Answers (Q&A)

What Oral Antidiabetic stimulates beta cells to secrete more insulin and increase receptor sites in the tissue?
E. Austin
Answered: Jun 20, 2019
Sulfonylureas. They are a class of organic compounds. Sulfonylureas are used in both fields of agriculture and medicine. The common drug that they are found in is the drug to manage type 2...Read More

5 Answers

577 views
When would a patient with an edema have an increased volume of distribution (Vd)?
Chris Kenway, Content Writer
Answered: Feb 01, 2019
The answer to this is letter C. There are some people who are not too familiar with hydrophilic drugs. This type of drugs usually stays in the blood until the extra fluid becomes eliminated. This...Read More

4 Answers

496 views
Which of the following is the least common drug-receptor bond? Drugs can bind to receptors via different types of chemical bonds.
John Smith
Answered: Oct 01, 2020
Covalent-5) learning objective: describe the different drug -receptor bonds.answer: ein general drugs binding to receptors in a reversible way and therefore the chemical bondbetween drug and...Read More

1 Answer

395 views
A drug with a half life of 12 hours is administered by continuous intravenous infusion. How long will IT take for the drug to reach 90 percent of its final steady state level?
John Smith
Answered: Oct 01, 2020
40 hours

3.3 x t1/2= 3.3x12= about 40 hours

1 Answer

358 views
Which statement about phenytoin is accurate?
John Smith
Answered: Oct 01, 2020
Toxic effects may occur with only small increments in dose

Sulfonamides can displace phenytoin from its binding sites, increasing the plasma-free fraction of the drug. Induction of liver...Read More

2 Answers

335 views
What was the content of a single tablet if the A1%,1cm was 490? 20 Carbamazepine tablets were found to weigh 10.000g in total. The tablets were ground to a fine powder using a pestle and mortar. A...
John Adney
Answered: Jul 12, 2017

C=0.588/490=0.0012g/100ml

0.0012/100=0.000012g in 1ml

0.000012df=0.0006g in the original

%=0.001/0.5100=20

2 Answers

323 views
A 47-year-old woman has been diagnosed with open-angle glaucoma. Pilocarpine drops are prescribed. The nurses assessment reveals that the patient has worn soft contact lenses for 15 years. The...
John Smith
Answered: Oct 01, 2020
Remove the contact lenses before applying the drops

1 Answer

314 views
Which of the following describes minimal effective concentration (MEC)?
M. Porter, Senior Executive
Answered: Dec 14, 2018
The answer is D. The minimal drug plasma concentration to produce effect describes minimal effective concentration (MEC). This question can often be tested in pharmacology or potentially in...Read More

2 Answers

300 views
Which of the following is not a side effect of the cholinoreceptor blocker (Atropine)?
Bergeront Tiffney, Computer Engineer
Answered: May 01, 2019
Atropine is an antimuscarinic receptor blocker that is commonly used to treat bradycardia and ophthalmic conditions. It is also used as an antidote to treat the toxicity of Acetylcholine esterase...Read More

3 Answers

292 views
What are cardiac glycosides?
Malcolm Carneal, Digital Nomad
Answered: Aug 23, 2018
Cardiac glycosides are special glycosides that have a special effect on the heart. They often increase the contractile force of the heart but decrease the rate of contractions. Hence, the heart...Read More

1 Answer

285 views
What type of cells to macrophages become as they engulf more and more cholesterol, becoming large and vacuolated?
Cmb
Answered: Oct 01, 2020
C and E.

1 Answer

280 views
Is IT apparent that there are spare receptors comparing the two graphs? Graphs B and C show Physiological effect vs concentration and Binding vs concentration for the same drug respectively.
Uncadf
Answered: Oct 01, 2020
No

Spare receptors occur when Emax occurs at less than 100% binding. In other words, when EC50 is less than Kd, spare receptors are present. The two are equal in this figure.

1 Answer

278 views
What stimulates rapid and short lived release of insulin from the pancreas?
Kcupery
Answered: Oct 01, 2020
Meglitinides

1 Answer

264 views
A 32-year-old cocaine addict was brought to the hospital 3 hours after self-injecting (IV) an unknown dose of cocaine. At admission the plasma level of cocaine was 1.25 mg/L. Pharmacokinetics data...
Chachelly
Answered: Oct 01, 2020
1.4g

T1/2 is 1 hr. therefore 3 hrs ago plasma concentration was 10mg/L (1.25x2x2x2) 10mg/L x 140L = 1400mg or 1.4grams.

1 Answer

251 views
What is the milligram equivalent dose in the following? The nurse is giving morning medications. The Medication Administration Record has an order for “levothyroxine, 75 mcg PO.” The...
John Smith
Answered: Oct 01, 2020
0.075 mg

There are 1000 mcg in 1 mg.

2 Answers

250 views

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